domain-specific fine-tuning
Assessing Large Language Models for Structured Medical Order Extraction
Karim, A H M Rezaul, Uzuner, Ozlem
Medical order extraction is essential for structuring actionable clinical information, supporting decision-making, and enabling downstream applications such as documentation and workflow automation. Orders may be embedded in diverse sources, including electronic health records, discharge summaries, and multi-turn doctor-patient dialogues, and can span categories such as medications, laboratory tests, imaging studies, and follow-up actions. The MEDIQA-OE 2025 shared task focuses on extracting structured medical orders from extended conversational transcripts, requiring the identification of order type, description, reason, and provenance. We present the MasonNLP submission, which ranked 5th among 17 participating teams with 105 total submissions. Our approach uses a general-purpose, instruction-tuned LLaMA-4 17B model without domain-specific fine-tuning, guided by a single in-context example. This few-shot configuration achieved an average F1 score of 37.76, with notable improvements in reason and provenance accuracy. These results demonstrate that large, non-domain-specific LLMs, when paired with effective prompt engineering, can serve as strong, scalable baselines for specialized clinical NLP tasks.
Understanding the Effects of Domain Finetuning on LLMs
Tanwar, Eshaan, Nathani, Deepak, Wang, William Yang, Chakraborty, Tanmoy
Large Language Models (LLMs) fine-tuned for specific domains exhibit strong performance; however, the underlying mechanisms by which this fine-tuning reshapes their parametric space are not well understood. Prior works primarily focus on auto-regressive or general-purpose instruct models, leaving domain-specialised LLMs under-explored. We present the first systematic study of domain-specific fine-tuning in large medical language models. Our analysis reveals that fine-tuning modifies only a small subset of the representational subspace, essentially preserving the pre-trained model's representation. To interpret these changes in subspaces, we propose tuning vectors, a novel framework inspired by task vectors, which explicitly capture the directional parameter shifts induced by fine-tuning. We demonstrate that these vectors are critical for enhancing both instruction-following and generation quality. Furthermore, combining tuning vectors across different domains yields improved generalisation. Upon closer inspection of directional alignment, we find these vectors primarily write new directional information into the MLP layers of the model, while amplifying existing directions in attention heads. Our findings offer new insights into LLM adaptation and provide a general, interpretable framework for analysing specialisation in large language models.
Do LLMs Understand Romanian Driving Laws? A Study on Multimodal and Fine-Tuned Question Answering
Barbu, Eduard, Dumitran, Adrian Marius
Ensuring that both new and experienced drivers master current traffic rules is critical to road safety. This paper evaluates Large Language Models (LLMs) on Romanian driving-law QA with explanation generation. We release a 1{,}208-question dataset (387 multimodal) and compare text-only and multimodal SOTA systems, then measure the impact of domain-specific fine-tuning for Llama 3.1-8B-Instruct and RoLlama 3.1-8B-Instruct. SOTA models perform well, but fine-tuned 8B models are competitive. Textual descriptions of images outperform direct visual input. Finally, an LLM-as-a-Judge assesses explanation quality, revealing self-preference bias. The study informs explainable QA for less-resourced languages.
Domain-Specific Fine-Tuning of Large Language Models for Interactive Robot Programming
Alt, Benjamin, Keßner, Urs, Taranovic, Aleksandar, Katic, Darko, Hermann, Andreas, Jäkel, Rainer, Neumann, Gerhard
Industrial robots are applied in a widening range of industries, but robot programming mostly remains a task limited to programming experts. We propose a natural language-based assistant for programming of advanced, industrial robotic applications and investigate strategies for domain-specific fine-tuning of foundation models with limited data and compute.